LOCUS       reptomyces_RBGC_677475 16094 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_677475
VERSION     Streptomyces_RBGC_677475
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001888885.1
  ORGANISM  GCF_001888885.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1635)
                     /protein_domains="PF00005"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622133"
                     /pseudo=False
                     /translation="MSFASIVASQLSFAWPDDTPVFQNLSFTVGPGRTGLVAPNGSGKS
                     TLLKLIAGQLRPAAGSVTVTGTAGYLPQDLPLTADLTVAEVLGVAEVIRAIDAVEAGDV
                     AEEHFTTIGDDWDIEERCRAQLERLGLGALRLDRGLAALSGGQIVQLGLAAQLLKRPDV
                     LLLDEPTNNLDLGARHRLYDALEDFGGCLLLVSHDRALLDRMDRIAELDSHELRLYGGD
                     FTAYEQAVQAEREVAEKNVRNAEQELKREKREMQQARERAERRAGNAARNLKSAGLPRI
                     FAGNMKRGAQESAGRAGQMHAARVDEAKARLDEAGRAVRDEQRLTLDLSGTKVPSGRDL
                     FIGEHLQVLRGGAPLFAGGGVDLTVRGPERIALSGANGAGKTTLLRLLVGDLTPDGGQV
                     KRADGRVAHLSQRLDLLDPDRTVAENFAAAAPERPEAERMNLLARFLFRGARAHLPVRA
                     LSGGERLRATLACVLCAEPAPQLLLLDEPTNNLDLVSVGQLEGALNSYQGAFLVVSHDE
                     RFLAGIGVDRWLRLADGELVEGGAPSA*"
     CDS             2040..2272
                     /protein_domains="PF00171"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622134"
                     /pseudo=False
                     /translation="VFADVDNSMRIAQEEIFGPVLVVIPYEGEDDAVRIANDSEYGLSG
                     GVWSTSEEHTDGFWRRVMPDAMSLLGHALATV*"
     CDS             2387..3348
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622135"
                     /pseudo=False
                     /translation="MEDTQPAVRARGLTKCFGDVVALDEVGLELVPGRIHGLAGPNGAG
                     KTTLLGLLLGLAVADGGELEVLGRPVGRALAAPDGVAGFVDGPGLYPSLTARKNLAALA
                     ALRGQDTGARRIDEVLAEVGLTDVADDRVRGFSLGMRQRLGLAAALLTEPRLLVLDEPS
                     NGLDPAGKQHVHGALRRLADNGVTVVLSSHRMDDLEALCSEVTILATGRVRFSGPLGTL
                     AVETRALDHRLLTSDLRTARLVAAGAAGVTVLDGDVAWRGTEVLVVRATAPAVEQLVAA
                     LVREGVGVREVAPVVSPLEAAYLALTQEQRTEEQQEYGR*"
     CDS             3346..4283
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622136"
                     /pseudo=False
                     /translation="MSTVTAGKAAAGPAAGPATRRVPVGRVYRFELVKLVSQWRIRLLV
                     LACWALPGLFVAAVAQQGTLPSDTLFGRWMHATGWAGPLVVLGFAGSWALPGYAFVSWN
                     GLFADPARLTELLIAVAVSLVWAVVATTAARVLFLRRDFTNGSEDGGGRRALAFGAAPL
                     AGLLALTFGAVAVATPSTGSGITQAKVQRTVTTVFAHLYRLQTEQLHRPTVTEADLRVT
                     ADCGRGDGQVDPEGPGNDWRCTVTWHLPGTAAPGTAIYQLDVASDGRVMADGDGPKEVN
                     GYFLVHTGAGDAPNPLWQFDGQVDLLASPTG*"
     CDS             4392..7144
                     /protein_domains="PF04185"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622137"
                     /pseudo=False
                     /translation="MQVTRRRRVRNEHPGRPGRRSGRRAVLATACITAVAVATGTAFAA
                     THQFGNDQVGQVTADGQVISSDQYLAPYGDRLVINNGKIMGSRVSPDGTHLAASLADGD
                     ASLVVVDLRTGKVQQRAGKARTADLKLTDGSVGQEAPVYSPDGRQLWLGQLDGYTRFTV
                     KADGSLADPVKVAIPADGDKHALASGAVFSADGSTLYAAVNGQNRVVAINTATGALGQS
                     WTVGNAPRGIVQVGHKLYVSNEGGRPATPDDDTLNSYGTQVPADPDTGAATSGTVSVID
                     LSAPSAAVGSIDVGLHPTAVYAKNGTVFVADTSSDQVSVIDTGRDKVVQRISTKPWPEA
                     SVGYEPTAVTLTDDGRLLVTLGRANAVAVYRFTSAQEPVSYVGLLPTDYFPAEVTTVGP
                     KVVVSNTRGIDARRPNSTGAHNTHDTTSSLTQFTLPGDKEIRSQTEKVFQQNGWTKNAV
                     RTADRRGAKPVAVPARIGDPSTIKHVFLIVKENRTYDQVFGDIGKGNGDPKLAQFGANV
                     TPNQQALAKQFGLYDNTYDIGTNSAEGHNWLMQADNPEYTESSAGEYERSYDTEDDALG
                     HQRSGFLWTGAQAAGQDVRDFGEFHQFLTKPDGANWQNLYCDAKNMDATGDDTAYPLNS
                     SSPIPSLNDVSVPGFPKFDLDVPDQYRYQIWKQDFEQNGPAALNMLWLSSDHTGGPASP
                     AAQVADNDLAVGRIVQEISHSEYWKDSAIFVVEDDSQAGLDHVDGHRAPIQIISPWAQH
                     GAVDSRYYSQITMVRTIEQILGIHPMNQKDSAATPMATAFTDKPDYTPFTAVPNRTSLT
                     DGLKTPPSCGVDVPGGAQDRSAVAAPVTAAPPAAEQGVAAQWDTWKSKQHLTGPNAAPD
                     RANPAQMNHLTWYQTHNWTTPYPGEDEIHTPDDVPGAYIPSAENDG*"
     CDS             complement(7229..10794)
                     /protein_domains="PF07733"
                     /protein_domains="PF17657"
                     /protein_domains="PF02811"
                     /protein_domains="PF14579"
                     /protein_domains="PF01336"
                     /protein_domains="TIGR00594"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622138"
                     /pseudo=False
                     /translation="VSDSFAHLHVHTEYSMLDGAAKNGKLFAEAERQGMPAIAMSDHGN
                     MFGAYEFFHAAAKTGVKPIIGIEAYVAPGSRFLKKQVFWSPGGQRPTGADGEGGKDVSG
                     GGRYTHMTMWAQNATGLRNLFKLSSLASMEGYYMKPRMDRELIAANAGGIIATTGCPSG
                     EVQTRLRLGQYEEAVKAAAAYQDIFGKENYFLELMDHGLDIERDVREDLLRLAKQLNIP
                     LLATNDSHYVTADQADAHDSLLCVGVGKNKDDPNRFKFQGTGYYVKTAEEMRALFRELP
                     EACDNTLAIAERVESYEEVFTYVDRMPQFDVPEGETQASYLRKKIEVGLKHRYGDNPSQ
                     EVLDRIELEMGVITPMGFDAYFLVVADICQYGRDNGIPVGPGRGSAAGSMIAYLTGITQ
                     LDPLEHDLLFERFLNPERINPPDVDIDFDDRQRDQMVRYVTEKYGAAYTAQVNTFGTIK
                     AKAAVKDANRILGYPFSMGDRITKAMPPDVMGKGVPLADLFDEKHARYNEGTEIRALYQ
                     NEPDVKKIIDTGRGIEGLIRGTGVHAAAVILSSTPLLDLIPLHMRDKDGVIITGFDYPS
                     CEAMGLIKMDFLGLRNLGIIDHCIKIVKANRGIDVDIEKIPIDDPTTYQLLARGDTLGV
                     FQLDGGPMRALLKLMKPTEFADISAVSALYRPGPMGMNSHTNYALRKNAQQEIIPIHPE
                     LEEPLKDVLGPTYGLIVYQEQVQRAAQVLAGYSLGQADLLRRAMGKKKKEVLEKEFVPF
                     HAGCKERGYSDEAIQAVWDVLVPFAGYAFNKSHSAAYGLVSYHTAYLKANYPAEYMAAL
                     LTSVADDKDKMAVYLAECRQMGIKILSPDVNESVVDFTAVGSDVRFGLKAVRNVGVPVI
                     ESLVGTREEKGKYTSFADFLDKVELVVCNKRTVDSLIKAGAFDSLGHTRLSLSSVHESA
                     IDSVTGLKKQQAIGQDDLFGALDPGDGGGPGIGLDFQLTDNEWPRRQLLALEREMLGLY
                     VSSHPLDGAEHILSQNRDTSIAELLGSGRSEGEVRLSGLITGVDRRINKAGNAWAIITL
                     ADRDGSVEVLFFPATYNLMADQMIEDNVISIRGRLNERDGSLSVFGQEITTLDVSSAEL
                     GTKPPVQITVPVHRITPQMVAELKLALQAHPGDVPIRLLTTNWDKNTLYELGFLVNPDN
                     GLASDIKTLLGNRAWTGAAVRS*"
     CDS             complement(10921..11609)
                     /protein_domains="PF13419"
                     /protein_domains="TIGR03351"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622139"
                     /pseudo=False
                     /translation="VIELAALDMAGTTINESGAVYRALRTAVERNGVAVAEADLQAWMG
                     TDKREAIAALVRLGGGTPTPELVEESYAAFAEYLREAYRTTPPQAVPGVEEALAELRRR
                     GIKVALTTGFSGDVAYPLLESLGWSTGEGGNLDAVVTSDEVPRGRPAPYMIHRAMQKTG
                     VIDTRRVLTAGDTVVDVEAGRNAGAGVVVGVLTGELGRADFDGHPQTHVLASAAEIPGL
                     AEARPSA*"
     CDS             complement(11615..12375)
                     /protein_domains="PF07702"
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622140"
                     /pseudo=False
                     /translation="VKTSEDLPLHQRLGAEFQRRIESGEWPEGEPVPSESQLCAEFGTS
                     RGPVRQALAMLRSAGSLVGGRGKPPVARRTTPSQPFDTFLSFTQWARSIGREPGQHTLE
                     VARRRASPEAAVRLGLAQDEPVVELVRLRLLDGVPAMLERSTFVHEVGRILFDFDPDTG
                     SVYQELLRREVDLHHARHTIDAVAAGPRDAELLRVDAGAPLLRVRRLTTSRLGVPLEDA
                     DDRYLPAMATFTIENTIEGRTVIGRYRTEED*"
     CDS             complement(12409..12551)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MLLLMGPASGRAGAGVKTCMYKLPTVHPPDDLSDLPGEQENPQLD
                     RS"
     CDS             12539..13428
                     /protein_domains="PF01266"
                     /protein_domains="PF01266"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622141"
                     /pseudo=False
                     /translation="MSSSTPPVTSPTTPRSDVVIVGAGIIGLAHAFEALSNGLSVTVLD
                     RDRRPVGASVRNFGHCCISAQDGELLALGPLAGLDAALELGAEFQRRIESGTVHTTRGP
                     VHGDRNLVCVGHDLDYLLPDVAEDHGIQRCRLTMARAAAPEGFRTDSAVLTATSMLRYD
                     AFTARPSAARLREEVLGHSAELLEIGANVMFTRQPDGTLLIGDSHHYDATTPPFVDERT
                     YELLIDAVARVLGVPRLRILERWQGVYASSPRGPLLVRDLAPGVRAISVTSGIGMTLSF
                     GLAAATFDGTLAATA*"
     CDS             complement(13501..14258)
                     /protein_domains="PF11716"
                     /protein_domains="PF07398"
                     /protein_domains="TIGR03083"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622142"
                     /pseudo=False
                     /translation="MTPLDHGTAVAAETARFVAAVRQADPALPVPGCPGWTLADLVRHT
                     GSVQRWFTVLLRQRIQEPPRSRDVDLRLPERPEDYPAWLAEAAEQAAAAFAEGDLDAPM
                     WAWGADQHARFWVRRMLFETLVHRVDAERALGLEPEIDPALAADGVDEFLTNLPFAAFF
                     APATAELRAENRTVRFARTDGEGDWLVRLRPDGFGLDHADTDTEAAATVRATAAELLLM
                     LYGRLDRDTAGVELSGDQELLAHWFAHSSF*"
     CDS             complement(14423..14796)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622143"
                     /pseudo=False
                     /translation="LTSDPGPGVLAHLGSLLHQAPADRSGALWRLQEESRQLDANIIRL
                     PANAEVAGHVEPDLDVLVQVLDGSGRLETANGRQDLSPGCTAWLPHGARRSVTAGGDGL
                     VYLTVHRRRPGLSIRSAPAE*"
     CDS             complement(14940..15361)
                     /protein_domains="PF04686"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622144"
                     /pseudo=False
                     /translation="MQLSTVRPLSVTFPESAAPDVPVEAELRFDASLPYAACLAFPLTP
                     CQCTGDEARVSWYFSRELLNEGRLGPVGSGDVKVRPGVAGEVLISLRGPGGGSLVSAPE
                     DLVTAFLSDSFTLVPAGSESDHLDIDAALARLLATD*"
     CDS             15652..16094
                     /protein_domains="PF13473"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_622145"
                     /pseudo=False
                     /translation="VTRSRPLRAAAALLLPAVLAACSSSGSGSGTPSTTATSPLQGSTV
                     ATSPVQSSAAAASPAQSSTAALQVTIKDFAFAPATLKAGPGRTVTVTNQDTTAHTLTAA
                     DKSFDTGTIAPGATATFTAPQQAGDHPYICTIHPFMHGTLTVG*"
ORIGIN
        1 tcacgcgctc ggggcgccgc cctccaccaa ctcgccgtcc gccagccgca gccagcggtc
       61 gacgccgatg ccggccagga agcgttcgtc gtgactgacc accaggaagg cgccctggta
      121 ggagttgagg gcgccttcga gctgcccgac gctgaccagg tccaggttgt tcgtcggctc
      181 gtccagcagc agcagctggg gcgcgggctc ggcgcacagc acgcaggcca gggtggcgcg
      241 cagccgctcg ccgccggaca gcgcccggac gggcaggtgg gcccgggcgc cgcggaacag
      301 gaagcgggcg agcaggttca tccgctcggc ctccggccgc tccggcgcgg cggcggcgaa
      361 gttctccgcc accgtgcggt ccgggtccag caggtccagg cgctgggaga ggtgggcgac
      421 ccggccgtcg gcccgcttga cctgcccgcc gtccggggtg aggtcgccga ccagcagccg
      481 cagcagggtg gtcttgccgg ccccgttggc gccggacagg gcgatccgct ccggacctcg
      541 aacggtcagg tcgacgccgc ccccggcgaa cagtggggcg ccgccgcgca gcacctggag
      601 gtgttcgccg atgaagaggt cgcggccgct cggcaccttg gtgccggaca ggtcgagggt
      661 gaggcgctgt tcgtcgcgca cggcgcgccc cgcctcgtcg agccgggcct tggcctcgtc
      721 gacccgggcg gcgtgcatct ggccggcccg cccggcggac tcctgggcgc cgcgcttcat
      781 gttcccggcg aagatgcggg gcagcccggc gctcttgagg ttgcgggcgg cgttgcccgc
      841 ccggcgctcg gcgcgttcgc gggcctgctg catctcccgc ttctcccgct tgagctcctg
      901 ctcggcgttg cggacgttct tctccgcgac ctcccgctcg gcctggacgg cctgctcgta
      961 ggcggtgaag tcgccgccgt agagccgcag ttcgtgcgag tcgagttcgg cgatccggtc
     1021 catccggtcg agcagggcgc ggtcgtggct gaccagcagg aggcagccgc cgaagtcctc
     1081 cagcgcgtcg tacagccggt ggcgggcccc gaggtcgagg ttgttggtgg gttcgtcgag
     1141 cagcaggacg tccggccgct tgagcagttg ggcggcgagg cccagttgca cgatctggcc
     1201 gccgctgagg gctgccaggc cccggtcgag gcgcagggcg ccgaggccga ggcgttcgag
     1261 ctgggcacgg cagcgctcct cgatgtccca gtcgtcaccg atggtggtga agtgctcctc
     1321 ggcgacgtcc cccgcctcca cggcgtcgat cgcccggatc acctcggcga cgccgagcac
     1381 ctcggcgacg gtgaggtcgg ccgtcagcgg gaggtcctgg gggaggtagc cggccgtgcc
     1441 ggtgaccgtc accgagccgg ccgccgggcg cagttgaccg gcgatcagct tgagcagcgt
     1501 gctcttgccc gaaccgttgg gcgcgaccag gccggtgcgg ccggggccga cggtgaagga
     1561 gaggttctgg aagacggggg tgtcgtcggg ccaggcgaag gacagctggg acgcgacgat
     1621 ggatgcgaag gacatgggaa cgacccggaa ggtgagcggg cggaaacgag tccggcccgg
     1681 gaaagacagg gggactgggg tacgacgagt ccgaccgctg caccgggcgc cctgcacccg
     1741 caacggccgt caagtccggg tctcacccgg agatgtcgtc gtcacccgcc atgtctgctg
     1801 cactcctccg aaggggttgg ttcgccagcg tagcagtcca cttcgccggg cgccgcccgt
     1861 ttttccgcgc gggttcgggg cccgtgcggt gaacggaacg gccccggccc ggtgggctcc
     1921 ggcctcaggg gtggccggcg tcagaggtgg tcggcgtcga cgacggcctg ggcgaaggcg
     1981 gtcggcgcct cctgggggac gttctggccg ataccggcca gcgtccggtg ctccgactgt
     2041 gttcgccgac gtcgacaact cgatgcggat cgcccaggag gagatcttcg gcccggtcct
     2101 ggtggtcatc ccctacgagg gcgaggacga cgccgtccgg atcgccaacg actccgagta
     2161 cggtctgtcc ggcggcgtct ggtccaccag cgaggagcac acggacggct tctggcggcg
     2221 ggtgatgccc gacgcgatgt cgctcctggg gcacgcgctc gccaccgtct gagccctcgg
     2281 cagcctccgg aacgaccgtc agctgttcca ccggtgttca accacgcggt ctcgactccg
     2341 tcccgtcaac cccctacctt ccctggggga ctgcgagaag gagccatgga agacacccaa
     2401 cctgccgtac gggcacgcgg attgacgaag tgcttcggtg acgtcgtggc gctcgacgag
     2461 gtcgggctgg agctggtacc cgggcggatc cacgggctgg ccgggccgaa cggcgccggg
     2521 aagaccacgc tgctggggct gctgctcggg ctggccgtcg ccgacggcgg cgagctggag
     2581 gtgctgggca gaccggtcgg acgggcactc gcggcgccgg acggggtcgc cggattcgtc
     2641 gacggccccg gcctgtaccc gtcgctgacc gcccggaaga acctggccgc gctggcggcg
     2701 ctgcgcggtc aggacaccgg ggcccggcgg atcgacgagg tgctggccga ggtcgggctg
     2761 accgacgtcg ccgacgaccg ggtgcggggc ttctcgctgg gcatgcgaca gcggctcggc
     2821 ctggccgccg cgctgctcac cgagccgcgg ctgctggtgc tcgacgagcc ctccaacggc
     2881 ctggacccgg cgggcaagca gcacgtgcac ggggcgctgc gccggctcgc ggacaacggc
     2941 gtgacggtcg tgctgtccag ccaccggatg gacgacctgg aggcgctctg ctccgaggtg
     3001 acgatcctcg cgaccgggcg ggtgcgattc tccggcccgc tgggcacgtt ggccgtcgag
     3061 acccgcgcgc tcgaccaccg gctgctcacc tccgacctgc gcaccgcgcg gctggtggcc
     3121 gccggggctg ccggggtgac ggtcctggac ggggacgtcg cgtggcgcgg cacggaggtc
     3181 ctggtggtgc gcgccaccgc gccggccgtc gaacagctgg tggcggcgct ggtacgggag
     3241 ggcgtagggg tgcgcgaggt cgcccccgtc gtgtcgccgc tggaggccgc gtacctcgcc
     3301 ctcacccagg agcagcgcac cgaggagcag caggagtacg ggcgatgagc acggtcacgg
     3361 ccgggaaggc ggcggccggt ccggccgccg ggcccgcgac gcgccgggtg ccggtgggcc
     3421 gggtgtaccg cttcgagctg gtcaagctcg tctcgcagtg gcggatccgc ctgctggtgc
     3481 tggcctgctg ggcgctgccc gggctgttcg tggcggccgt ggcccagcag gggacactgc
     3541 cctccgacac cctgttcggc cgctggatgc acgccaccgg ctgggccggt ccgttggtgg
     3601 tgctgggctt cgccggctcc tgggcgctgc ccggctacgc cttcgtctcg tggaacggtt
     3661 tgttcgccga tccggcacgt ctgaccgagc tgctgatcgc cgtcgcggtg agcctggtgt
     3721 gggcggtggt ggcgaccacc gcggcccgtg tgctgttcct ccggcgggac ttcaccaacg
     3781 gcagcgagga cggcggcggt cgccgggcgc tcgccttcgg ggcggccccg ctggccgggc
     3841 tgctggcgct gaccttcggc gcggtcgccg tggccacgcc ctcgaccggg tcggggatca
     3901 cccaggcgaa ggtgcagcgc acggtcacca ccgtgttcgc gcacctgtac cggctgcaga
     3961 ccgagcagtt gcaccgcccc accgtcaccg aggccgacct gcgggtcacg gcggactgcg
     4021 gccggggcga cggccaggtc gacccggagg ggccgggcaa cgactggcgc tgcaccgtca
     4081 cctggcacct gcccggtact gccgctccgg ggacggcgat ctaccagctg gacgtcgcct
     4141 cggacgggcg ggtgatggcg gacggggacg gcccgaagga agtgaacggc tacttcctgg
     4201 tgcacaccgg ggccggcgac gcgccgaacc cgctctggca gttcgacggc caggtcgacc
     4261 tgctcgcctc cccgaccggc tgaccgggca ccagcgccgg caccggcacc ggcacaccga
     4321 agctcccacg ctcccacgca tccccgcgcg ctcaccacga agcgcgcact cacaacgaag
     4381 ggctgacgcc atgcaggtaa cgcgtcgtcg acgtgtccgc aacgagcacc ccgggcgccc
     4441 cggccggcgg tcgggccgcc gggccgtgct ggccacggcg tgcatcacgg cggtggccgt
     4501 ggccaccggc acggccttcg cggccaccca ccagttcggc aacgaccagg tcggccaggt
     4561 caccgccgac ggccaggtga tctccagcga ccagtacctg gccccgtacg gcgaccggct
     4621 ggtgatcaac aacggcaaga tcatgggctc ccgggtcagc ccggacggca cccacctggc
     4681 cgcctcgctc gccgacggcg acgcctcgct ggtcgtggtg gacctgagga ccggcaaggt
     4741 gcagcagcgt gcgggcaagg caaggacggc cgacctgaag ctgaccgacg gctcggtcgg
     4801 ccaggaggcc ccggtctact cgccggacgg caggcagctc tggctgggcc agctcgacgg
     4861 ctacacccgg ttcaccgtca aggccgacgg ttccctggcc gacccggtga aggtggcgat
     4921 cccggccgac ggcgacaagc acgcgcttgc ctccggcgcg gtgttctccg ccgacggctc
     4981 gacgctgtac gcggcggtca acggccagaa ccgggtggtc gcgatcaaca cggccaccgg
     5041 cgcgctcggg cagagctgga cggtgggcaa cgcgccccgc ggcatcgtgc aggtcgggca
     5101 caagctgtac gtcagcaacg agggcggccg ccccgccacc cccgacgacg acaccctcaa
     5161 ctcctacggc acccaggtcc cggccgaccc ggacaccggc gccgcgacct cgggcaccgt
     5221 cagcgtgatc gacctctccg ccccgtccgc cgccgtcggc tcgatcgacg tcggcctgca
     5281 cccgaccgcg gtgtacgcca agaacgggac ggtcttcgtc gccgacacct cctccgacca
     5341 ggtgtcggtc atcgacaccg ggcgcgacaa ggtggtgcag cggatctcca ccaagccgtg
     5401 gccggaggcc tcggtgggct atgagccgac ggcggtgacc ctcaccgacg acggacgcct
     5461 gctggtcacc ctcggccgcg ccaacgcggt ggcggtctac cgcttcacca gcgcccagga
     5521 gccggtgagt tacgtcggcc tgctgcccac cgactacttc ccggccgagg tcaccaccgt
     5581 cggcccgaag gtggtcgtct ccaacacccg cggcatcgat gcccggcgcc ccaactccac
     5641 cggcgcccac aacacccacg acaccacctc cagcctgacc cagttcaccc tgccgggcga
     5701 caaggagatc cgctcccaga ccgagaaggt cttccagcag aacggctgga cgaagaacgc
     5761 ggttcggacg gccgaccggc gcggggctaa gcccgtggcc gtaccggccc ggatcggcga
     5821 cccgtcgacg atcaagcacg tcttcctgat cgtcaaggag aaccggacct acgaccaggt
     5881 cttcggcgac atcggcaagg gcaacggtga cccgaagctg gcccagttcg gcgccaacgt
     5941 gacgcccaac cagcaggcgc tggccaagca gttcgggctc tacgacaaca cctacgacat
     6001 cggcaccaac tccgccgagg gccacaactg gctgatgcag gcggacaacc cggagtacac
     6061 cgagtcctcc gcgggcgagt acgagcgcag ctacgacacc gaggacgacg ccctggggca
     6121 ccagcgctcg ggcttcctgt ggacgggcgc gcaggcggcc ggccaggacg tgcgcgactt
     6181 cggcgagttc caccagttcc tgaccaagcc cgacggcgcg aactggcaga acctgtactg
     6241 cgacgccaag aacatggacg cgaccggcga cgacaccgcc tacccgctca actcctcctc
     6301 gccgatcccg tcgctcaacg acgtgtcggt gcccggcttc cccaagttcg acctcgacgt
     6361 gcccgaccag taccgctacc agatctggaa gcaggacttc gagcagaacg gcccggccgc
     6421 gctcaacatg ctctggctgt ccagcgacca caccggcggg ccggccagcc cggccgcgca
     6481 ggtcgccgac aacgacctgg cggtcggcag gatcgtccag gagatctcgc acagcgagta
     6541 ctggaaggac tccgcgatct tcgtggtcga ggacgactcc caggccggcc tggaccacgt
     6601 ggacggccac cgcgccccga tccagatcat cagcccctgg gcccagcacg gcgccgtcga
     6661 cagccgctac tactcgcaga tcaccatggt ccgcaccatc gagcagatcc tcgggatcca
     6721 cccgatgaac cagaaggaca gcgcggccac gccgatggcc acggccttca ccgacaagcc
     6781 cgactacacc ccgttcaccg cggtgcccaa ccggacctcg ctgaccgacg gcctgaagac
     6841 cccgccctcc tgcggcgtcg acgtgcccgg cggggcccag gaccgcagcg cggtggcggc
     6901 gccggtgacc gccgccccgc cggcggccga gcagggcgtc gccgcccagt gggacacctg
     6961 gaagtccaag cagcacctga ccggccccaa cgccgccccg gaccgcgcga acccggccca
     7021 gatgaaccac ctgacctggt accagaccca caactggacc acgccgtacc cgggcgagga
     7081 cgagatccac accccggacg acgtccccgg cgcctacatc ccctccgccg agaacgacgg
     7141 ctgacaccct ccccgaggac cgtgaacggg ccccggagcg gctccaaccg gtccggggcc
     7201 cgtacgtgtc ccatcgagga cagggcccta cgagcgcacc gccgcgcccg tccaggcccg
     7261 gttgccgagg agggtcttga tgtccgaggc gagcccgttg tcggggttca ccaggaagcc
     7321 cagctcgtag agggtgttct tgtcccagtt ggtggtgagc agccggatcg ggacgtcgcc
     7381 ggggtgggcc tggagtgcga gcttgagctc ggcgaccatc tggggggtga tccggtggac
     7441 cgggacggtg atctggaccg gcggcttggt gccgagttcg gcggaggaga cgtcgagggt
     7501 ggtgatctcc tggccgaaga cgctcagcga gccgtcgcgc tcgttgagcc ggccgcggat
     7561 cgagatcacg ttgtcctcga tcatctggtc ggccatcagg ttgtaggtcg cggggaagaa
     7621 cagcacctcg accgagccgt cgcggtcggc gagggtgatg atcgcccagg cgttgcccgc
     7681 cttgttgatc cgccggtcga cgccggtgat cagcccggac agccggacct cgccctcgga
     7741 gcggccggag ccgaggagtt cggcgatcga ggtgtcgcgg ttctgggaca ggatgtgctc
     7801 ggcgccgtcg agcgggtggc tggagacgta caggccgagc atctcccgct ccagggcgag
     7861 gagttggcgc cgaggccact cgttgtcggt gagctggaag tccagtccga tgccgggccc
     7921 gccgccgtcg ccggggtcga gggcgccgaa caggtcgtcc tggccgatgg cctgctgctt
     7981 cttcagcccg gtgacggagt cgatcgcgct ctcgtggacg ctgctgagcg agagccgggt
     8041 gtggccgagc gagtcgaagg cgcccgcctt gatcagggag tcgacggtgc gcttgttgca
     8101 gaccaccagc tcgaccttgt ccaggaagtc ggcgaaggaa gtgtacttgc ccttctcttc
     8161 ccgggtgccg accagcgact cgatcacggg cacgccgacg ttgcgcacgg ccttgaggcc
     8221 gaagcggacg tcgctgccga cggcggtgaa gtcgaccacc gactcgttga cgtcggggga
     8281 gaggatcttg atgcccatct gccggcactc ggccaggtag acggccatct tgtccttgtc
     8341 gtcggcgacg gaggtgagca gcgcggccat gtactcggcc gggtagttgg ccttcaggta
     8401 ggcggtgtgg taggagacca ggccgtaggc ggcggagtgc gacttgttga acgcgtagcc
     8461 ggcgaacggg accaggacgt cccagaccgc ctggatggcc tcgtcggaat agccgcgctc
     8521 cttgcagccc gcgtggaagg gcacgaactc cttctccagc acctccttct tcttcttgcc
     8581 catcgcgcgg cgcagcaggt ctgcctggcc gagtgagtag ccggccagca cctgggccgc
     8641 tcgctggacc tgctcctggt agacgatcag gccgtaggtg gggccgagga cgtccttgag
     8701 cggttcctcc agctcggggt ggatcgggat gatctcctgc tgggcgttct tgcgcagcgc
     8761 gtagttggtg tgcgagttca tgcccatcgg gccgggccgg tacagcgcgg agacggcgga
     8821 gatgtcggcg aactcggtgg gcttcatcag cttgagcagg gcgcgcatgg ggccgccgtc
     8881 gagctggaac acgcccaggg tgtcgccgcg ggcgagcagc tggtaggtgg tggggtcgtc
     8941 gatcgggatc ttctcgatgt cgacgtcgat gccccggttg gccttcacga tcttgatgca
     9001 gtggtcgatg atgcccaggt tccgcagacc caggaagtcc atcttgatca ggcccatggc
     9061 ttcgcaggac gggtagtcga agccggtgat gatcaccccg tccttgtccc gcatgtgcag
     9121 cgggatcagg tcgagcagcg gggtggagga gaggatgacg gcggccgcgt gcacgccggt
     9181 gccgcggatc aggccctcga tgccgcgccc ggtgtcgatg atcttcttga cgtccggttc
     9241 gttctggtac agcgcccgga tctcggtgcc ctcgttgtac cgggcgtgct tctcgtcgaa
     9301 caggtcggcc agcggcacgc ccttgcccat gacgtccggc ggcatcgcct tggtgatccg
     9361 gtcgcccatc gagaacgggt agcccaggat gcggttggcg tccttgacgg cggccttggc
     9421 cttgatggtg ccgaaggtgt tcacctgcgc cgtgtacgcg gcgccgtact tctcggtgac
     9481 gtagcgcacc atctggtcgc gctggcggtc gtcgaagtcg atgtcgacgt ccggggggtt
     9541 gatgcgctcg gggttgagga agcgctcgaa caacaggtcg tgctccagcg ggtccagttg
     9601 ggtgatcccg gtcaggtagg cgatcatcga gccggcggcc gagccacggc cggggccgac
     9661 cgggatgccg ttgtcccggc cgtactggca gatgtcggcg accacgagga agtaggcgtc
     9721 gaaccccatc ggggtgatga cgcccatctc cagctcgatc cggtccagca cctcctggct
     9781 cgggttgtcg ccgtagcggt gcttcagccc gacctcgatc ttcttgcgca ggtaggaggc
     9841 ctgggtctcg ccctcgggca cgtcgaactg gggcatccgg tcgacgtagg tgaagacctc
     9901 ctcgtacgac tcgacccgct cggcgatcgc cagggtgttg tcgcaggcct ccggcagttc
     9961 gcggaagagc gcgcgcatct cctcggcggt cttcacgtag tagccggtgc cctggaactt
    10021 gaagcggttc gggtcgtcct tgttcttgcc cacgccgacg cagagcaggc tgtcgtgggc
    10081 gtcggcctgg tcagcggtga cgtagtggga gtcgttggtg gccagcagcg ggatgttcag
    10141 ctgcttggcc agccgcagca ggtcctcgcg gacgtcgcgc tcgatgtcca ggccgtggtc
    10201 catcagctcc aggaagtagt tctccttccc gaagatgtcc tggtacgcgg cggcggcctt
    10261 gaccgcctcc tcgtactggc ccagccgcag ccgggtctgc acctcgccgg aggggcagcc
    10321 ggtggtcgcg atgatgccgc cggcgttggc ggcgatcagc tcgcggtcca tccggggctt
    10381 catgtagtag ccctccatcg acgcgaggga ggacagcttg aagaggttcc gcaggccggt
    10441 cgcgttctgc gcccacatcg tcatgtgggt gtagcggccg ccgccggaga cgtccttgcc
    10501 gccctcaccg tcggcgccgg tcgggcgctg gccgcccggc gaccagaaca cctgcttttt
    10561 caggaagcgc gagccggggg cgacgtacgc ctcgatgccg atgatcggct tcacgccggt
    10621 cttcgcggcg gcgtggaaga actcgtacgc gccgaacatg ttgccgtggt cgctcatcgc
    10681 gatggcgggc atgccctgtc tctccgcctc ggcgaacagc ttgccattct tcgccgcccc
    10741 gtccagcatc gagtactcgg tgtggacgtg caggtgcgcg aagctgtcgg acacggcgct
    10801 gctctccttg gtgggcgtcg gtagggcgaa gcggtccacg ctagcgggtc ggcgcgcgcg
    10861 acgcacgacg ggctgacgga ccgccctgcg acggcccggc agcccgtgcg ggggaaccgt
    10921 caggcgctcg gccgggcctc ggcgaggccg gggatctcgg cggcgctggc cagcacgtgg
    10981 gtctgcgggt gcccgtcgaa gtcggcgcgg ccgagctccc cggtcagcac cccgacgacc
    11041 acgccggccc cggcgttgcg cccggcctcg acgtcgacca cggtgtcacc ggccgtcagc
    11101 acccggcggg tgtcgatcac cccggtcttc tgcatcgccc ggtggatcat gtacggggcc
    11161 ggacggccgc gcggcacctc gtccgaggtc accaccgcgt caaggttgcc gccctcgccg
    11221 gtggaccagc cgagcgactc cagcagcggg tacgcgacgt cgccgctgaa gccggtggtg
    11281 agcgcgacct tgatcccgcg gcggcgcagc tcggccagcg cctcctcgac cccggggacg
    11341 gcctgtgggg gagtggtccg gtaggcctcg cgcaggtact ccgcgaaggc cgcgtagctc
    11401 tcctccacca gctccggggt cggggtgccg ccgccgaggc ggaccagggc ggcgatggcc
    11461 tcgcgcttgt cggtgcccat ccaggcctgg aggtcggcct cggcgacggc cacaccgttg
    11521 cgttcgacgg cggtgcgcag cgcccggtag acggcgccgg actcgttgat ggtggtcccg
    11581 gccatgtcca gggcggcgag ctcgatcacg gtgtcagtcc tcttcggtgc ggtagcggcc
    11641 gatgacggta cggccttcga tggtgttctc gatggtgaag gtggccatgg cgggcaggta
    11701 gcggtcgtcg gcgtcctcca gcggcacgcc caggcgggag gtggtgagcc ggcgtacccg
    11761 cagcagcggg gctccggcgt cgacccgcag cagttcggcg tcgcgcggcc cggcggcgac
    11821 ggcgtcgatg gtgtgccgcg cgtggtggag gtcgacctcg cggcgcagca gttcctggta
    11881 gacggagccg gtgtccgggt cgaagtcgaa caggatgcgg ccgacctcgt ggacgaaggt
    11941 ggagcgctcc agcatggccg ggacgccgtc cagcagccgc agccggacga gttcgacgac
    12001 cggctcgtcc tgcgcgaggc ccagccggac cgccgcctcc ggggaggccc ggcggcgggc
    12061 gacctcgagg gtgtgctgcc cgggctcgcg gccgatgctg cgggcccact gggtgaagga
    12121 caggaaggtg tcgaagggct gggagggcgt ggtgcgacgg gccacgggcg gcttcccgcg
    12181 cccgccgacc aggctgcccg cgctgcgcag catggccagg gcttggcgga ccggcccccg
    12241 ggaggtgccg aactcggcgc agagctgcga ctcgctgggc accggctcgc cctcgggcca
    12301 ctcgccggac tcgatgcggc gctggaactc ggcgccgagc cgttggtgga gggggaggtc
    12361 ctcacttgtc ttcacaagtc gactatggca cccgggccca ggacttctca agaccgatcg
    12421 agctgcggat tctcctgttc acccggcaga tcactgagat cgtcgggcgg atgaacagtc
    12481 ggtaacttgt acatacatgt cttgacgcca gcgcccgccc gcccggaagc tggacccatg
    12541 agcagcagca ccccacccgt gacctccccc accaccccgc gcagcgatgt ggtgatcgtc
    12601 ggcgccggaa tcatcggcct cgcccacgcc ttcgaggcgc tgagcaacgg actctccgtc
    12661 accgtcctcg accgcgaccg gcggccggtc ggcgcctccg tccgcaactt cggccactgc
    12721 tgcatcagcg cccaggacgg cgaactgctc gccctcgggc cactcgccgg actcgatgcg
    12781 gcgctggaac tcggcgccga gttccagcgc cgcatcgagt ccggcaccgt gcacaccacc
    12841 cgcggcccgg tccacggcga ccgcaatctg gtctgcgtcg gccacgacct ggactacctg
    12901 ctccccgacg tcgccgagga ccacgggatc cagcgctgcc ggctgaccat ggcccgggcc
    12961 gccgccccgg agggcttccg caccgactcc gcggtgctga ccgccacctc gatgctgcgc
    13021 tacgacgcct tcaccgcccg gccatcggct gcccggctgc gggaggaggt gctcggccac
    13081 agcgcggagc tgctggagat cggcgcgaac gtgatgttca cccgccagcc ggacggcacc
    13141 ctgctgatcg gcgactcgca ccactatgac gccaccaccc cgccgttcgt cgacgagcgc
    13201 acctacgagc tgctgatcga cgccgtcgcc cgggtgctgg gcgtgccgcg gctgcggatc
    13261 ctggagcgct ggcagggcgt ctacgccagc agcccccgcg ggccgctgct ggtgcgcgac
    13321 ctggccccgg gggtgcgggc catctcggtc acctcgggca tcgggatgac cctctccttc
    13381 ggcctcgcgg ccgccacctt cgacggcacc ctcgccgcga cggcctgagc cgctgcccat
    13441 cggtgctcgg aagtcccgtc ggtgctcgaa ggcggtcggt gctcggaagg tggtcgtgct
    13501 cagaaggacg agtgggcgaa ccagtgcgcc agcagttcct ggtcgccgga gagctcgaca
    13561 ccggcggtgt cgcggtcgag gcgcccgtac agcatgagca gcagttcggc ggcggtggcg
    13621 cggacggtgg cagcggcctc cgtgtcggtg tcggcgtggt cgaggccgaa gccgtcgggg
    13681 cgcagccgga ccagccagtc gccctcgccg tcggtgcggg cgaagcggac ggtccggttc
    13741 tcggcgcgca gttcggccgt cgcgggggcg aagaaggcgg cgaagggcag gttggtcagg
    13801 aactcgtcca ccccgtcggc cgcgagggcc gggtcgatct ccggctccag tccgagcgcg
    13861 cgttcggcgt cgacccggtg gacgagggtc tcgaacagca tccggcgcac ccagaaccgg
    13921 gcgtgctggt cggcgcccca ggcccacatc ggcgcgtcga ggtcgccctc ggcgaaggcc
    13981 gcggcggcct gttcggcggc ctcggccagc caggccgggt agtcctccgg ccgctcgggc
    14041 agccgcaggt cgacgtcccg gctgcgcggc ggctcctgga tccgctggcg cagcaggacg
    14101 gtgaaccagc gctgcacgct gccggtgtgg cggacgaggt cggcgagcgt ccaccccggg
    14161 cagccgggga ccgggagggc ggggtcggcc tgccgcacgg cggcgacgaa gcgggcggtc
    14221 tcggcggcga cggcggtgcc gtggtccagc ggggtcatca gggctgcctc tcaattcttc
    14281 atgtagtgaa gcaattgcga cgacgctagg cctgaaaggt tgaggctgtc aagtaactct
    14341 cgggtgcgct ccggccccgg agatcgccgg cccagagggc gggtggcttc gccgcagcgg
    14401 gacctacccc cacggccgta ctcactcggc gggcgccgag cggatggaca ggcctggccg
    14461 gcggcggtgg acggtgaggt agaccagtcc gtccccgccc gccgtgacgg accgccgggc
    14521 gccgtgcggc agccaggccg tgcaccccgg ggagaggtcc tggcggccgt tggcggtctc
    14581 cagccgaccg ctcccgtcga gcacctggac caggacgtcg aggtccggct ccacgtgccc
    14641 ggcgacctcg gcgttcgcgg gcaggcggat gatgttcgcg tccagctggc ggctctcctc
    14701 ctggaggcgc cacagcgctc cgctgcggtc ggcgggagcc tggtggagca gggaccccag
    14761 gtgggcgagc acaccggggc cgggatcgga cgtcaacgag gcctcctgcg ggcgagtggg
    14821 atcggcccgt ggattctacg gaggatcgca cgcgacccgg acggccggcg ggcccggtcg
    14881 ctggtcccac tcggtgggcc cggtcgctgg tctcgctcgg tgggcccggt cggcgggctc
    14941 agtcggtggc gaggagccgg gcgagggccg cgtcgatgtc caggtggtcg gactcggagc
    15001 cggccggcac cagggtgaag gagtccgaga ggaacgccgt gacgaggtcc tccggtgcgc
    15061 tgaccaggga cccgccgccg ggcccccgca ggctgatcag gacctcgccc gccacccccg
    15121 gacggacctt cacgtcgccg ctgccgaccg ggccgagccg cccctcgttc agcagctcac
    15181 ggctgaagta ccaggacacc cgggcttcgt cgccggtgca ctggcacgga gtcagcggaa
    15241 aggccaggca ggccgcataa gggaggctcg cgtcgaagcg gagctccgcc tcgaccggaa
    15301 cgtcgggcgc cgcgctctcc gggaaggtca cggacagcgg gcggacggtg gacaactgca
    15361 tcgattcggc ctcctgcgat cgcaacggcc ggcccgcggc ggtccggctg cccatggcgc
    15421 ctacccggcg cgccgagaca cagccagggg cggacgaatc tccacaattc ccttgcatca
    15481 ccggcctgca ccgcccgccg gcaggcgtca actccgcgcc cgcttcttca ctcctgcgca
    15541 tgaaatggtg ggccgtccgg agctctggag caggtcacgg cggcctcctg ccggaggagg
    15601 ctggccagtg ggccgctccc gccgcccgcc ctcccgaacg gagcccgaac gtgaccagat
    15661 cccggcccct ccgggcagcc gccgcgctgc tgctccccgc cgtcctcgcg gcctgctcca
    15721 gctcgggctc cggctccgga acgccgtcga ccaccgcgac gagccccctg cagggcagca
    15781 ccgtcgcgac gagtcccgtc cagagcagtg ccgccgccgc gagccccgcc cagagcagta
    15841 ccgcggcgct ccaggtcacc atcaaggact tcgccttcgc gcccgcgacc ctgaaggcgg
    15901 gccccggccg gaccgtcacc gtgacgaacc aggacaccac cgcccacacc ctcaccgccg
    15961 ccgacaagtc cttcgacacc gggacgatcg cgcccggcgc caccgcgacc ttcaccgcgc
    16021 cccagcaggc cggcgaccac ccgtacatct gcaccatcca cccgttcatg cacggcaccc
    16081 tcaccgtggg ctga
//
